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. 2021 Nov;10(11):4664–4679. doi: 10.21037/tcr-21-1646

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2021 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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Genetic mutations of XPO1. (A) Mutation frequencies of XPO1 in the 33 tumor types. Correlations of XPO1 expression with expression levels of the top 30 highly mutated genes in (B) BLCA, (C) CESC, (D) CHOL, (E) COAD, (F) GBM, (G) LAML, (H) MESO, (I) PRAD, (J) READ, (K) TGCT, and (L) UCEC. Circle size indicates the magnitude of the P value and shade indicates the magnitude of the Spearman’s rank correlation coefficient. XPO1, Exportin 1; BLCA, bladder carcinoma; CESC, cervical squamous cell carcinoma and endocervical adenocarcinoma; CHOL, cholangiocarcinoma; COAD, colon adenocarcinoma; GBM, glioblastoma multiforme; LAML, acute myeloid leukemia; MESO, mesothelioma; PRAD, prostate adenocarcinoma; READ, rectum adenocarcinoma; TGCT, testicular germ cell tumor; UCEC, uterine corpus endometrial carcinoma.