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| TCGA subgroup | Mutation profile | Frequency |
|---|---|---|
| POLE ultramutated | PTEN | 94% |
| FBXW7 | 82% | |
| ARID 1A | 76% | |
| PIK3CA | 71% | |
| PIK3R1 | 65% | |
| KRAS | 53% | |
| ARID5B | 47% | |
| Microsatellite instability hypermutated | PTEN | 88% |
| PIK3CA | 54% | |
| KRAS | 35% | |
| PIK3R1 | 40% | |
| ARID 1A | 37% | |
| RPL22 | 33% | |
| Copy number low | PTEN | 77% |
| PIK3CA | 53% | |
| CTNNB1 | 52% | |
| ARID1A | 42% | |
| PIK3R1 | 33% | |
| Copy number high | TP53 | 92% |
| PIK3CA | 47% | |
| PPP2R1A | 22% |
TCGA, The Cancer Genome Atlas.
