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. 2021 Dec;10(12):5267–5279. doi: 10.21037/tcr-21-1441

Table 2. Univariate survival analysis of clinicopathological features in 363 patients with CRC (log-rank test).

Variables All cases Mean survival (months) Chi-square value P valued
Gender 0.915 0.339
   Female 154 94.34±3.93
   Male 209 99.33±3.22
Age1, years 6.26 0.012a
   ≤60 183 102.32±3.41
   >60 180 91.87±3.62
Tumor size2 0.122 0.727
   ≤4 cm 192 99.43±3.27
   >4 cm 171 94.73±3.82
Tumor differentiation 7.95 0.005b
   Well 32 113.24±6.06
   Moderate 307 97.67±2.68
   Poor 24 67.88±11.21
Infiltration type 1.778 0.182
   Infiltration 19 82.67±10.56
   Ulcerative 206 96.20±3.32
   Uplift 138 99.42±3.95
pT stage 31.19 0.000c
   T1 10 119.50±8.33
   T2 81 115.20±4.04
   T3 106 106.28±4.04
   T4 166 80.44±3.93
pN stage 34.66 0.000c
   N0 206 109.05±2.77
   N1 103 88.98±4.85
   N2 54 64.87±7.15
pM stage 59.65 0.000c
   M0 295 105.33±2.44
   M1 68 58.79±6.38
Clinical stage 52.21 0.000c
   I 66 118.45±3.81
   II 123 108.24±3.37
   III 106 92.25±4.65
   IV 68 58.79±6.38
Relapse 84.67 0.000c
   No 287 106.76±2.62
   Yes 76 59.44±4.52
Vascular invasion 64.59 0.000c
   No 255 109.61±2.54
   Yes 108 68.01±4.81
Nerve invasion 37.26 0.000c
   No 224 109.26±2.71
   Yes 139 76.76±4.28
Serosa invasion 36.43 0.000c
   No 195 111.46±2.85
   Yes 168 80.71±3.89
CFIm25 expression 14.97 0.000c
   Low 219 88.53±3.38
   High 144 110.69±3.32

Age1: median; Tumor size2: median; aP<0.05, bP<0.01, cP<0.001. dLog-rank test. CRC, colorectal cancer; CFIm25, Cleavage Factor Im 25.