Table 2. Univariate survival analysis of clinicopathological features in 363 patients with CRC (log-rank test).
| Variables | All cases | Mean survival (months) | Chi-square value | P valued |
|---|---|---|---|---|
| Gender | 0.915 | 0.339 | ||
| Female | 154 | 94.34±3.93 | ||
| Male | 209 | 99.33±3.22 | ||
| Age1, years | 6.26 | 0.012a | ||
| ≤60 | 183 | 102.32±3.41 | ||
| >60 | 180 | 91.87±3.62 | ||
| Tumor size2 | 0.122 | 0.727 | ||
| ≤4 cm | 192 | 99.43±3.27 | ||
| >4 cm | 171 | 94.73±3.82 | ||
| Tumor differentiation | 7.95 | 0.005b | ||
| Well | 32 | 113.24±6.06 | ||
| Moderate | 307 | 97.67±2.68 | ||
| Poor | 24 | 67.88±11.21 | ||
| Infiltration type | 1.778 | 0.182 | ||
| Infiltration | 19 | 82.67±10.56 | ||
| Ulcerative | 206 | 96.20±3.32 | ||
| Uplift | 138 | 99.42±3.95 | ||
| pT stage | 31.19 | 0.000c | ||
| T1 | 10 | 119.50±8.33 | ||
| T2 | 81 | 115.20±4.04 | ||
| T3 | 106 | 106.28±4.04 | ||
| T4 | 166 | 80.44±3.93 | ||
| pN stage | 34.66 | 0.000c | ||
| N0 | 206 | 109.05±2.77 | ||
| N1 | 103 | 88.98±4.85 | ||
| N2 | 54 | 64.87±7.15 | ||
| pM stage | 59.65 | 0.000c | ||
| M0 | 295 | 105.33±2.44 | ||
| M1 | 68 | 58.79±6.38 | ||
| Clinical stage | 52.21 | 0.000c | ||
| I | 66 | 118.45±3.81 | ||
| II | 123 | 108.24±3.37 | ||
| III | 106 | 92.25±4.65 | ||
| IV | 68 | 58.79±6.38 | ||
| Relapse | 84.67 | 0.000c | ||
| No | 287 | 106.76±2.62 | ||
| Yes | 76 | 59.44±4.52 | ||
| Vascular invasion | 64.59 | 0.000c | ||
| No | 255 | 109.61±2.54 | ||
| Yes | 108 | 68.01±4.81 | ||
| Nerve invasion | 37.26 | 0.000c | ||
| No | 224 | 109.26±2.71 | ||
| Yes | 139 | 76.76±4.28 | ||
| Serosa invasion | 36.43 | 0.000c | ||
| No | 195 | 111.46±2.85 | ||
| Yes | 168 | 80.71±3.89 | ||
| CFIm25 expression | 14.97 | 0.000c | ||
| Low | 219 | 88.53±3.38 | ||
| High | 144 | 110.69±3.32 |
Age1: median; Tumor size2: median; aP<0.05, bP<0.01, cP<0.001. dLog-rank test. CRC, colorectal cancer; CFIm25, Cleavage Factor Im 25.