Table 1. Univariate and multivariate Cox proportional hazards model predicting survival in ccRCC patients.

Variables	Univariate analysis			Multivariate analysis
	HR (95% CI)	P value		HR (95% CI)	P value
Age		0.017			0.160
>60 vs. ≤60	1.497 (1.074–2.085)			1.404 (0.875–2.253)
Gender		0.605			0.665
Male vs. female	0.914 (0.651–1.284)			1.112 (0.689–1.795)
T stage		0.000			0.111
T3/T4 vs. T1/T2	3.091 (2.215–4.314)			2.221 (0.831–5.933)
Lymph node metastasis		0.008			0.377
N1 vs. N0	2.853 (1.308–6.225)			1.459 (0.631–3.377)
Distant metastasis		0.000			0.002
M1 vs. M0	4.827 (3.441–6.769)			2.589 (1.421–4.717)
Clinical stage		0.000			0.849
III/IV vs. I/II	3.815 (2.694–5.403)			0.900 (0.302–2.680)
Grade		0.000			0.047
G4/G3 vs. G1/G2	2.650 (1.822–3.854)			1.709 (1.008–2.899)
PTPRO expression		0.039			0.005
Low vs. high	1.415 (1.017–1.969)			1.955 (1.224–3.122)

ccRCC, clear cell renal cell carcinoma; G, grade; T, tumor; N, node; M, metastasis; HR, hazard ratio; CI, confidence interval.