Table 5. Drug relations of CHEK1, CDK1 and TOP2A.

Gene name	No.	Drug bank ID	Name	Drug group	Pharmacological action	Actions
CHEK1	1	DB12010	Fostamatinib	Approved, investigational	Unknown	Inhibitor
CDK1	1	DB12010	Fostamatinib	Approved, investigational	Unknown	Inhibitor
	2	DB04014	Alsterpaullone	Experimental	Unknown	Inhibitor
	3	DB02116	Olomoucine	Experimental	Unknown	Binder
	4	DB02052	Indirubin-3'-monoxime	Experimental	Unknown	Binder
	5	DB03428	SU9516	Experimental	Unknown	Binder
TOP2A	1	DB00218	Moxifloxacin	Approved, investigational	Unknown	Inhibitor
	2	DB00276	Amsacrine	Approved, investigational	Yes	Inhibitor
	3	DB00380	Dexrazoxane	Approved, withdrawn	Yes	Inhibitor
	4	DB00385	Valrubicin	Approved	Yes	Inhibitor
	5	DB00444	Teniposide	Approved	Yes	Inhibitor
	6	DB00445	Epirubicin	Approved	Unknown	Inhibitor
	7	DB00467	Enoxacin	Approved, investigational	No	Inhibitor
	8	DB00487	Pefloxacin	Approved	Unknown	Inhibitor
	9	DB00694	Daunorubicin	Approved	Unknown	Inhibitor
	10	DB00773	Etoposide	Approved	Unknown	Inhibitor
	11	DB00970	Dactinomycin	Approved, investigational	Yes	Inhibitor
	12	DB00978	Lomefloxacin	Approved, investigational	Yes	Inhibitor
	13	DB00997	Doxorubicin	Approved, investigational	Unknown	Inhibitor
	14	DB01059	Norfloxacin	Approved	Unknown	Inhibitor
	15	DB01137	Levofloxacin	Approved, investigational	Yes	Inhibitor
	16	DB01165	Ofloxacin	Approved	Unknown	Inhibitor
	17	DB01177	Idarubicin	Approved	Yes	Inhibitor
	18	DB01179	Podofilox	Approved	Yes	Inhibitor
	19	DB01204	Mitoxantrone	Approved, investigational	Yes	Inhibitor
	20	DB01208	Sparfloxacin	Approved, investigational, withdrawn	Yes	Inhibitor
	21	DB04576	Fleroxacin	Experimental	Yes	Inhibitor
	22	DB04967	Lucanthone	Investigational	Yes	Inhibitor
	23	DB06013	Aldoxorubicin	Investigational	Yes	Inhibitor
	24	DB09047	Finafloxacin	Approved, investigational	Yes	Inhibitor