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. 2019 Apr;8(2):410–421. doi: 10.21037/tcr.2019.02.03

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2019 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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Apoptosis of the A549 cell line. (A) Dot plot scattergrams for the: (a) Control group, (b) NC group, (c) siRHAMM group, (d) Control + R group, (e) NC + R group, and (f) siRHAMM + R group; (B) histogram showing the higher apoptotic rate in the siRHAMM group (19.57%±2.51%) compared with the Control and NC groups (1.67%±0.30% and 2.42%±0.66%, respectively). *, P<0.05 vs. Control group; ^#, P<0.05 vs. NC group. The apoptotic rate was higher in the siRHAMM + R group (24.81%±3.05%) than in the siRHAMM, Control + R (3.45%±1.73%), and NC + R (5.71%±0.58%) groups. **, P<0.05 vs. siRHAMM group; ^$, P<0.05 vs. Control + R group; ^&, P<0.05 vs. NC + R group. RHAMM, receptor for hyaluronan-mediated motility; Control, mock transfection; NC, negative control; siRHAMM, RHAMM knockdown; R, radiation.