Table 2. Analysis for the optimal cutoff point of CRP, ferritin, LDH, and cytokines in serum.
| Variable | AUC | 95% CI | P value | Cutoff value | Sensibility | Specificity |
|---|---|---|---|---|---|---|
| LDH | 0.688 | 0.561–0.816 | 0.001 | 548 U/L | 0.462 | 0.968 |
| CRP | 0.754 | 0.637–0.871 | 0.001 | 25.35 µg/L | 0.462 | 0.962 |
| Ferritin | 0.707 | 0.578–0.835 | 0.005 | 323.25 mg/L | 0.795 | 0.577 |
| IL-2 | 0.552 | 0.408–0.696 | 0.487 | |||
| IL-4 | 0.570 | 0.429–0.711 | 0.346 | |||
| IL-6 | 0.833 | 0.728–0.937 | <0.001 | 15.920 pg/mL | 0.641 | 0.920 |
| IL-10 | 0.769 | 0.651–0.888 | <0.001 | 6.145 pg/mL | 0.692 | 0.800 |
| IL-17A | 0.481 | 0.339–0.622 | 0.794 | |||
| TNF-α | 0.728 | 0.604–0.852 | 0.002 | 0.275 pg/mL | 0.846 | 0.520 |
| IFN-γ | 0.588 | 0.446–0.729 | 0.239 |
LDH, lactate dehydrogenase; CRP, C-reactive protein; IL, interleukin; TNF-α, tumor necrosis factor-α; IFN-γ, interferon-γ.