Table S1. Demographic and clinical characteristics of the 24 healthy individuals enrolled in the study.
| Variable | Sample | Age (y) | Sex (0: male; 1: female) | Serum HIF-1ɑ levels in exosomes (pg/mL) | Serum exosome concentration (µg/μL) |
|---|---|---|---|---|---|
| Cohort of serum exosome concentration | 1 | 32 | 0 | 270.071 | 1.61574 |
| 2 | 42 | 0 | 250.244 | 2.904544 | |
| 3 | 45 | 0 | 223.031 | 1.05877 | |
| 4 | 48 | 0 | 287.376 | 4.070296 | |
| 5 | 39 | 0 | 268.144 | 4.627266 | |
| 6 | 34 | 1 | 302.856 | 2.885114 | |
| 7 | 37 | 0 | 270.071 | 0.9098124 | |
| 8 | 41 | 0 | 305.027 | 4.102678 | |
| 9 | 50 | 1 | 186.007 | 3.565136 | |
| Cohort of serum HIF-1ɑ levels in exosomes | 10 | 47 | 0 | 302.931 | – |
| 11 | 40 | 1 | 195.701 | – | |
| 12 | 36 | 1 | 279.541 | – | |
| 13 | 36 | 0 | 295.836 | – | |
| 14 | 38 | 1 | 258.989 | – | |
| 15 | 42 | 1 | 290.365 | – | |
| 16 | 44 | 0 | 188.644 | – | |
| 17 | 31 | 1 | 243.608 | – | |
| 18 | 35 | 0 | 235.875 | – | |
| 19 | 51 | 0 | 258.683 | – | |
| 20 | 47 | 1 | 204.702 | – | |
| 21 | 55 | 1 | 283.817 | – | |
| 22 | 37 | 0 | 179.351 | – | |
| 23 | 49 | 1 | 302.593 | – | |
| 24 | 32 | 1 | 210.876 | – |
HIF, hypoxia-inducible factor.