Table 4.

Relationship between periodontal pathogens in saliva, supragingival plaque, and subgingival plaque with the concentrations of the Aa and Pg antibodies, CRP and LPS.

		[CRP] (b)	[LPS] (b)	[anti-Aa] (b)	[anti-Pg] (b)
Sample (a)	Pathogen	Coefficient ± SE (c)	Coefficient ± SE (c)	Coefficient ± SE (c)	Coefficient ± SE (c)
Saliva	Aa	−0.034 ± 0.13	−0.007 ± 0.028	−0.0095 ± 0.017	–
	Pg	−0.075 ± 0.15	0.076 ± 0.035*	–	0.017 ± 0.026
Supragingival	Aa	0.066 ± 0.10	−0.029 ± 0.027	−0.017 ± 0.015	–
	Pg	−0.084 ± 0.15	0.062 ± 0.033	–	0.030 ± 0.027
Subgingival	Aa	−0.17 ± 0.12	−0.035 ± 0.029	−0.0049 ± 0.017	–
	Pg	−0.18 ± 0.15	0.071 ± 0.034*	–	0.014 ± 0.026

CRP, C-reactive protein; LPS, lipopolysaccharide; Aa, Aggregatibacter actinomycetemcomitans; Pg, Porphyromonas gingivalis.

Significant *(p < 0.05).

^(a)All periodonpathogens amounts expressed in log10 of number of genome equivalents (Geq/ml).

^(b)Log-transform applied to antibodies concentration, CRP and LPS.

^(c)Regression coefficients derived by linear regression adjusted for group (stable/unstable); a positive (negative) coefficient indicates an increasing (decreasing) relationship between pathogens and CRP, LPS and antibodies amount.