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. 2019 Oct;8(6):2252–2263. doi: 10.21037/tcr.2019.09.38

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2019 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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KIF18A can regulate the expression of EMT-related proteins. (A,B) The western blot experiment showed that KIF18A-overexpressed in Tu686 cells could up-regulate Vimentin expression and down-regulate E-cadherin expression; (C,D) the expression of Vimentin was decreased and the expression of E-cadherin was increased by the down-regulated KIF18A in 6-10B cells. **, P <0.01.