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. 2019 Jun;8(3):736–751. doi: 10.21037/tcr.2019.04.10

Table 13. Basic information of each mutation type of EGFR.

Clinicopathological features Classification EGFR mutation types
Exon 2 Exon 4 Exon 6 Exon 18 Exon 19 Exon 20 Exon 21 Exon 22 Amplification
Gender Male 1 1 0 1 13 6 9 1 7
Female 0 0 1 0 12 6 10 0 6
Age ≥60 1 1 0 1 11 5 8 1 6
<60 0 0 1 0 14 7 11 0 7
TNM staging IV 1 1 1 0 25 12 16 1 11
Non-IV 0 0 0 1 0 0 3 0 2
Smoking history Yes 1 1 0 1 12 5 7 1 8
No 0 0 1 0 13 7 12 0 5
Pathological type ADC 1 1 1 0 25 12 19 1 12
SCC 0 0 0 1 0 0 0 0 1

ADC, adenocarcinoma; SCC, squamous cell carcinoma.