Skip to main content
. 2020 Mar;9(3):1742–1751. doi: 10.21037/tcr.2020.03.26

Figure 3.

Figure 3

Knockdown PTEN counteracts the inhibitory effect of LSZ on the invasion and proliferation of LC cells. (A) The protein level of PTEN was detected by western blotting in H1299 cells infected with lentivirus holding LV3-NC or LV3-PTEN. (***, P<0.001 vs. LV3-NC group). (B) The mRNA level of PTEN was detected by RT-qPCR in H1299 cells infected with lentivirus holding LV3-NC or LV3-PTEN. (**, P<0.01 vs. LV3-NC group). (C,D) Normal H1299 cells and PTEN-deficient H1299 cells were treated with LSZ. (B) Invasive ability was measured by the Transwell assay. (C) Proliferative ability was measured by the clone formation assay. Magnification ×400 (***, P<0.001 vs. control group). LSZ, ligustrazine; LC, lung cancer.