Table 5. Univariate analysis of OS and DFS in patients stratified by treatment modality.
Variables | Both pre and postoperative chemotherapy | Preoperative chemotherapy only | |||
---|---|---|---|---|---|
P value for OS | P value for DFS | P value for OS | P value for DFS | ||
Age | 0.378 | 0.526 | 0.133 | 0.107 | |
Gender | 0.154 | 0.546 | 0.479 | 0.855 | |
ASA risk score | 0.209 | 0.115 | 0.116 | 0.014* | |
cT | 0.913 | 0.316 | 0.180 | 0.031* | |
cN | 0.448 | 0.239 | 0.281 | 0.479 | |
NAC regimens | 0.441 | 0.378 | 0.620 | 0.649 | |
No. of NAC cycles | 0.462 | 0.233 | 0.074 | 0.391 | |
Clinical response | 0.284 | 0.206 | 0.955 | 0.801 | |
NISN | 0.005* | 0.035* | 0.029* | 0.116 | |
Approach | 0.066 | 0.061 | 0.426 | 0.734 | |
Extent of gastrectomy | <0.001* | <0.001* | 0.004* | 0.019* | |
Additional organs resection | 0.594 | 0.436 | 0.366 | 0.243 | |
Tumor location | 0.043* | 0.014* | 0.338 | 0.361 | |
Differentiation | 0.002* | <0.001* | 0.018* | 0.009* | |
LVI | 0.018* | 0.007* | 0.087 | 0.052 | |
Residual tumor | 0.109 | 0.023* | 0.135 | 0.002* | |
Postop complications | 0.347 | 0.019* | 0.057 | 0.241 | |
HPR | 0.310 | 0.085 | 0.052 | 0.107 | |
pT category | <0.001* | <0.001* | 0.016* | 0.023* | |
pN category | 0.019* | 0.002* | 0.007* | 0.479 | |
No. of postop cycles | 0.020* | 0.092 | NA | NA |
*, results are shown statistically significant. OS, overall survival; DFS, disease-free survival; HR, hazard ratio; CI, confidence interval; ASA, American society of Anesthesiologists; NAC, neoadjuvant chemotherapy; LVI, lymphovascular invasion; HPR, histopathological response; postop, postoperative. NA, not available.