Table 3. Univariate and multivariate analyses of the prognostic factors of RFS for HCC after RFA.

Variables	Univariate				Multivariate
	HR	95% CI	P		HR	95% CI	P
Demographic factors
Age ≥55 years	1.02	0.85–1.26	0.12
Sex (male)	0.66	0.31–1.67	0.31
BMI ≥25 kg/m2	1.03	0.99–1.12	0.24
Liver cirrhosis	2.23	1.06–7.56	0.04		1.88	0.85–6.53	0.33
Child-Pugh stage	1.12	0.53–3.51	0.27
MELD scores	1.56	0.88–4.66	0.06
Tumor factors
AFP (ng/mL)	1.00	0.98–1.01	0.21
Tumor size (cm)	1.31	0.93–2.57	0.08
Laboratory tests
ALT	2.07	0.88–9.53	0.41
ALB	0.57	0.12–2.14	0.26
TB	2.89	1.05–8.57	0.03		2.61	1.22–8.31	0.06
PLT	1.00	0.98–1.02	0.37
PT	1.01	0.99–1.01	0.51
Fibrosis status
LSM ≥13.4 kPa	3.12	1.08–10.25	0.02		2.87	1.03–9.15	<0.01

RFS, recurrence-free survival; HCC, hepatocellular carcinoma; CI, confidence interval; HR, hazard ratio; BMI, body mass index; AFP, alpha-fetoprotein; ALT, alanine aminotransferase; ALB, albumin; TB, total bilirubin; PLT, platelet count; PT, prothrombin time; LSM, liver stiffness measurement; MELD, model for end-stage liver disease scores.