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. 2021 Jan;10(1):126–140. doi: 10.21037/tcr-20-2712

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2021 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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Differential expression of six candidate genes in AML samples and healthy volunteers was validated again in other data sets in GEO. The data was downloaded from GEO database, which was analyzed and visualized by GraphPad Prism 8.3.0. Non-paired sample t-test was used for statistical analysis. The relative mRNA expression of FLT3, PF4, CD163, MRC1, CSF2RB, PPBP in AML from GEO datasets: (A) FLT3; (B) PF4; (C) CD163; (D) MRC1; (E) CSF2RB; (F) PPBP. *, P<0.05; **, P<0.01; ***, P<0.001; ****, P<0.0001. FLT3, FMS-related tyrosine kinase 3; PF4, platelet factor 4; CD163, the macrophage scavenger receptor; MRC1, mannose receptor C-type 1; CSF2RB, colony stimulating factor 2 receptor subunit beta; PPBP, pro-platelet basic protein; AML, acute myeloid leukemia; GEO, Gene Expression Omnibus.