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. 2019 Apr;8(2):664–675. doi: 10.21037/tcr.2019.04.04

Table S1. Gene ontology biological process terms enriched in NPC-related genes.

Gene set Description No. of genes P value FDR
GO:0001667 Ameboidal-type cell migration 46 0 0
GO:0002521 Leukocyte differentiation 53 0 0
GO:0006979 Response to oxidative stress 53 0 0
GO:0007050 Cell cycle arrest 38 0 0
GO:0007159 Leukocyte cell-cell adhesion 64 0 0
GO:0007346 Regulation of mitotic cell cycle 67 0 0
GO:0007568 Aging 52 0 0
GO:0009314 Response to radiation 60 0 0
GO:0009612 Response to mechanical stimulus 35 0 0
GO:0009617 Response to bacterium 61 0 0
GO:0010035 Response to inorganic substance 57 0 0
GO:0022407 Regulation of cell-cell adhesion 53 0 0
GO:0033002 Muscle cell proliferation 39 0 0
GO:0033674 Positive regulation of kinase activity 57 0 0
GO:0040017 Positive regulation of locomotion 60 0 0
GO:0042493 Response to drug 58 0 0
GO:0044770 Cell cycle phase transition 62 0 0
GO:0045785 Positive regulation of cell adhesion 57 0 0
GO:0045787 Positive regulation of cell cycle 48 0 0
GO:0048514 Blood vessel morphogenesis 66 0 0
GO:0048545 Response to steroid hormone 48 0 0
GO:0048732 Gland development 59 0 0
GO:0050673 Epithelial cell proliferation 56 0 0
GO:0050900 Leukocyte migration 53 0 0
GO:0051052 Regulation of DNA metabolic process 48 0 0
GO:0051090 Regulation of sequence-specific DNA binding transcription factor activity 48 0 0
GO:0051098 Regulation of binding 45 0 0
GO:0051272 Positive regulation of cellular component movement 58 0 0
GO:0070482 Response to oxygen levels 55 0 0
GO:0070997 Neuron death 49 0 0
GO:0071216 Cellular response to biotic stimulus 38 0 0
GO:0071417 Cellular response to organonitrogen compound 55 0 0
GO:0071900 Regulation of protein serine/threonine kinase activity 57 0 0
GO:0090130 Tissue migration 41 0 0
GO:0097191 Extrinsic apoptotic signaling pathway 42 0 0
GO:0097193 Intrinsic apoptotic signaling pathway 41 0 0
GO:2001233 Regulation of apoptotic signaling pathway 55 0 0
GO:0031589 Cell-substrate adhesion 42 1.11E−16 2.23E−15
GO:0007369 Gastrulation 32 2.22E−16 4.34E−15
GO:0048144 Fibroblast proliferation 23 4.44E−16 8.46E−15
GO:0018212 Peptidyl-tyrosine modification 45 6.66E−16 1.24E−14
GO:0071559 Response to transforming growth factor beta 34 1.78E−15 3.22E−14
GO:0001101 Response to acid chemical 41 2.44E−15 4.23E−14
GO:0071214 Cellular response to abiotic stimulus 39 2.44E−15 4.23E−14
GO:0002764 Immune response-regulating signaling pathway 50 3.33E−15 5.64E−14
GO:0031349 Positive regulation of defense response 46 4.22E−15 6.99E−14
GO:1901652 Response to peptide 48 7.55E−15 1.22E−13
GO:0072331 Signal transduction by p53 class mediator 36 1.02E−14 1.62E−13
GO:0001819 Positive regulation of cytokine production 44 1.19E−14 1.85E−13