Table 2. Expression of MCT1 and MCT4 in different characteristics’ groups.
Variables | Patients, n | MCT4 expression | MCT1 expression | |||||
---|---|---|---|---|---|---|---|---|
Low, n (%) | High, n (%) | P value | Low, n (%) | High, n (%) | P value | |||
Age, y | 0.103 | 0.572 | ||||||
<60 | 51 | 24 (47.1) | 27 (52.9) | 42 (82.4) | 9 (17.6) | |||
≥60 | 49 | 31 (63.3) | 18 (36.7) | 43 (87.8) | 6 (12.2) | |||
Gender | 0.551 | 0.013* | ||||||
Male | 74 | 42 (56.8) | 32 (43.2) | 59 (79.7) | 15 (20.3) | |||
Female | 26 | 13 (50.0) | 13 (50.0) | 26 (100) | 0 (0) | |||
Pathological types | 0.166 | 0.000* | ||||||
Adenocarcinoma | 54 | 25 (46.3) | 29 (53.7) | 54 (100) | 0 (0) | |||
Squamous | 43 | 28 (65.1) | 15 (34.9) | 28 (65.1) | 15 (34.9) | |||
Others† | 3 | 2 (66.7) | 1 (33.3) | 3 (100) | 0 (0) | |||
Tumor differentiation | 0.872 | 0.117 | ||||||
Poor | 52 | 29 (55.8) | 23 (44.2) | 47 (90.4) | 5 (9.6) | |||
Moderate | 48 | 26 (54.2) | 22 (45.8) | 38 (79.2) | 10 (20.8) | |||
Stage | 0.746 | 0.688 | ||||||
I-II | 71 | 41 (57.7) | 30 (42.3) | 61 (85.9) | 10 (14.1) | |||
III-IV | 29 | 14 (48.3) | 15 (51.7) | 24 (82.8) | 5 (17.2) | |||
Smoking history | 0.358 | 0.003* | ||||||
Never | 33 | 16 (48.5) | 17 (51.5) | 33 (100) | 0 (0) | |||
Smoker | 67 | 39 (58.2) | 28 (41.8) | 52 (77.6) | 15 (22.4) |
†, others including adenosquamous carcinoma, large cell carcinoma, sarcoma, etc. Cross-table analysis with Chi-squared (χ2) tests were performed. *P<0.05.