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. 2020 Jan;9(1):222–230. doi: 10.21037/tcr.2019.12.72

Table 3. Severity of hyponatremia and hypercalcemia cases according to tumour stage.

Staging [n] Serum sodium (mEq/L) CSC (mmol/L)
Mild hyponatremia (130 to 135) Moderate hyponatremia (125 to 129) Severe hyponatremia (≤124) Total (% of n) Moderate hypercalcemia (2.63–2.99) Severe hypercalcemia (≥3.00) Total (% of n)
SCLC [102]
   Limited stage [28] 6 1 0 7 (25.0) 0 0 0 (0)
   Extensive stage [74] 24 4 7 35 (47.3) 4 0 4 (5.4)
TNM staging [522]
   Stage I/II [191] 32 5 4 41 (21.5) 6 1 7 (3.7)
   Stage IIIA [67] 16 3 0 19 (28.4) 8 1 9 (13.4)
   Stage IIIB/IV [264] 73 18 4 95 (36.0) 20 4 24 (9.1)