Skip to main content
. 2020 Apr;9(4):2482–2491. doi: 10.21037/tcr.2020.03.17

Figure 4.

Figure 4

miR-124 and MALAT1 inhibit each other in RAW 264.7 cells. (A) Sequence in which MALAT1 and miR-124 bind to each other; (B,C) dual luciferase gene reporter system validates sequence of direct binding of MALAT1 to miR-124; (D) miR-124 expressed in each group; (E) levels of Rab27a, IL-11, NFATc1 and TARP protein in RAW 264.7 cells after transferring to miR-NC or miR-124-mimic. Three times for each experiment, ***, P<0.001 vs. control group, and ###, P<0.001 vs. denosumab group. MALAT1, metastasis-associated lung adenocarcinoma transcript 1; NFATc1, activated T-cell nuclear factor 1; miR-NC, miR-negative control; TRAP, tartrate-resistant acid phosphatase.