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. 2020 Sep;9(9):5390–5400. doi: 10.21037/tcr-19-3022a

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2020 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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The effect of SERM combined with estrogen on the proliferation and apoptosis of uterine leiomyoma cells. (A) Results of PCNA protein band development through Western-Blot. (B) Contrast of PCNA protein gray value. (C) Results of Bcl-2 protein band development through Western-Blot. (D) Contrast of Bcl-2 protein gray value. TSEC group: estrogen (17-beta estradiol) + SERM (raloxifene), E+P group: estrogen (17-beta estradiol) + medroxyprogesterone acetate, E group: estrogen (17-beta estradiol) alone. *, stands for P<0.05, and the difference was statistically significant.