Table 3. Multivariate analysis results of different populations based on the COX proportional hazards model.
| Site of metastasis, n (%) | Treatment | OS | CSS | |||
|---|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |||
| Bone, 59 (11.0) | S or/and R + C | – | – | – | – | |
| C | 3.326 (1.168–9.468) | 0.024 | 3.139 (1.100–8.961) | 0.033 | ||
| S or/and R | 2.413 (0.929–6.268) | 0.070 | 2.405 (0.912–6.339) | 0.076 | ||
| N | 4.870 (1.823–13.011) | 0.002 | 4.493 (1.647–12.256) | 0.003 | ||
| Liver, 130 (24.2) | S or/and R + C | – | – | – | – | |
| C | 1.380 (0.757–2.514) | 0.293 | 1.380 (0.749–2.545) | 0.302 | ||
| S or/and R | 3.478 (1.581–7.649) | 0.002 | 3.533 (1.598–7.810) | 0.002 | ||
| N | 9.196 (4.649–18.190) | 0.000 | 9.218 (4.612–18.425) | 0.000 | ||
| Lung, 191 (35.6) | S or/and R + C | – | – | – | – | |
| C | 1.071 (0.586–1.957) | 0.825 | 1.020 (0.542–1.918) | 0.951 | ||
| S or/and R | 1.979 (1.398–3.631) | 0.001 | 2.262 (1.384–3.696) | 0.001 | ||
| N | 3.393 (2.221–5.185) | 0.000 | 3.238 (2.078–5.044) | 0.000 | ||
| Multiple, 149 (27.7) | S or/and R + C | – | – | – | – | |
| C | 1.092 (0.611–1.952) | 0.766 | 1.109 (0.617–1.995) | 0.729 | ||
| S or/and R | 3.391 (1.856–6.197) | 0.000 | 3.490 (1.902–6.404) | 0.000 | ||
| N | 4.702 (2.662–8.305) | 0.000 | 4.649 (2.609–8.286) | 0.000 | ||
OS, overall survival; CSS, cancer-specific survival; S, surgery; R, radiotherapy; C, chemotherapy; N, no treatment.