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| Up-regulated | Down-regulated | |||
|---|---|---|---|---|
| Gene | Degree | Gene | Degree | |
| MYC | 58 | ACTB | 29 | |
| STAT3 | 47 | CDK6 | 26 | |
| HSP90AA1 | 43 | DICER1 | 23 | |
| CDKN1A | 32 | CCNE1 | 22 | |
| HSPA4 | 28 | CDKN1B | 20 | |
| SMAD3 | 28 | CCND3 | 19 | |
| DICER1 | 27 | BCL2L1 | 19 | |
| FOXO3 | 27 | ATM | 19 | |
| CYCS | 25 | CREBBP | 19 | |
| SMAD2 | 24 | BIRC5 | 18 | |
| CDKN1B | 23 | CDH2 | 18 | |
| CCNA2 | 23 | ABL1 | 17 | |
| BCL2L11 | 23 | CCNF | 16 | |
| DNMT1 | 22 | BUB1 | 15 | |
| KDM6B | 22 | CCNE2 | 15 | |
| AGO2 | 21 | ACTN1 | 15 | |
| AGO1 | 20 | CD44 | 15 | |
| AURKB | 20 | AGO1 | 14 | |
| YWHAB | 20 | AXIN1 | 14 | |
| HSP90B1 | 20 | AGO2 | 14 | |
