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. 2021 Jun;10(6):2906–2917. doi: 10.21037/tcr-20-3341

Table 1. Clinical and pathologic features of colorectal cancer patients.

Feature (N=100) Variable N TFU of tumor P TFU of CAF P RTL P
Age (years) <65 64 1,535 (572–4,897) 0.245 2,885 (1,873–3,913) 0.046 0.73 (0.25–2.5) 0.815
≥65 36 2,718 (576–7,514) 2,317 (1,309–3,223) 0.99 (0.28–1.87)
Gender Male 45 2,082 (457–5,779) 0.967 2,600 (1,764–3,738) 0.386 0.71 (0.20–2.1) 0.406
Female 55 1,876 (655–4,315) 2,271 (1,575–3,337) 0.92 (0.37–2.0)
Tumor location Right colon 26 1,292 (334–5,726) 0.505 1,855 (739–2,831) 0.127 1.07 (0.31–3.20) 0.657
Left colon 74 2,082 (616–5,486) 2,437 (1,776–3,506) 0.92 (0.25–1.96)
Differentiation Well 54 2,189 (691–5,779) 0.260 2,437 (1767–3,542) 0.303 0.94 (0.29–2.30) 0.879
Moderate–poor 46 1,085 (481–5,709) 2,162 (1,268–2,993) 0.92 (0.18–1.92)
T stage T1-2 38 2,066 (698–6,235) 0.643 2,599 (1,964–3,581) 0.212 0.71 (0.25–2.53) 0.587
T3-4 62 1,879 (523–5,450) 2,254 (1,340–3,484) 0.94 (0.29–1.96)
Lymph node metastasis Negative 52 1,820 (669–4,715) 0.776 2,440 (1,764–3,463) 0.849 0.74 (0.26–1.97) 0.581
Positive 48 2,198 (516–7,500) 2,395 (1,529–3,508) 0.84 (0.29–2.15)
Perineural invasion Negative 97 1,994 (626–5,508) 0.021 2,451 (1,810–3,508) 0.001 0.89 (0.26–2.10) 0.577
Positive 3 360 (130–499) 404 (384–506) 0.71 (0.34–0.75)
lymphovascular invasion Negative 90 2,136 (631–5,666) 0.037 2,427 (1,776–3,451) 0.815 0.93 (0.29–2.53) 0.0662
Positive 10 676 (130–1,989) 2,173 (1,042–4,876) 0.35 (0.13–1.07)
Distant metastases Negative 89 2,314 (684–5,802) 0.002 2,550 (1,728–3,574) 0.208 0.98 (0.31–2.17) 0.020
Positive 11 557 (130–956) 2,156 (1,261–2,427) 0.23 (0.08–0.89)
Dukes stage A 29 1,943 (719–5,248) 0.023 2,550 (1,882–4,010) 0.447 0.74 (0.22–2.07) 0.072
B 21 1,765 (703–5,125) 2,368 (1,106–3,334) 0.99 (0.32–2.68)
C 39 2,759 (617–7,771) 2,799 (1,703–3,871) 1.08 (0.48–2.34)
D 11 557 (130–956) 2,156 (1,261–2,427) 0.23 (0.08–0.89)

TFU, telomere fluorescent intensity units; CAF, cancer-associated fibroblast cell; RTL, relative telomere length.