Table 2. Treatment and timeline of the present case.
| Month | Symptoms and diagnosis | Treatment |
|---|---|---|
| 1 | Bleeding in stool | |
| 2 | ||
| Day 1–11 | Ascending colon cancer (T3N0M0) | Hospitalization and laparoscopic radical operation |
| Day 12–27 | – | Discharge |
| Day 28 | Good physical and mental condition | 6 rounds of chemotherapy treatment: irinotecan 240 mg iv at the first day, S-1 capsule orally from day 1 to day 14 (80 mg/day, 2/d), 21 days for one round |
| 3–6 | – | – |
| 7 | ||
| Day 1–8 | Diarrhea (2–3 times daily till 7–10 times daily) | Discharge |
| Day 9 | Delirium and unclear consciousness, Grade 3 myelosuppression and Grade 4 diarrhea | G-CSF 300 μg sc daily |
| IL-11 6 mg sc daily | ||
| Loperamide 4 mg orally 2/d | ||
| NS 500 mL +10% KCl 3 g iv 2/d | ||
| Compound sodium chloride | ||
| Injection 500 mL iv 2/d | ||
| Imipenem 0.5 g iv 3/d | ||
| Day 10 | Arrhythmia, somnolence, low blood pressure and petechiae | Adrenaline 11 μg/kg/h, |
| Norepinephrine 22 μg/kg/h | ||
| Amiodarone 300 mg iv | ||
| Day 11 | Declared dead | – |
iv, intravenous; S-1, tegafur-gimeracil-oteracil potassium; G-CSF, granulocyte colony-stimulating factor; IL-11, recombinant human IL; sc, subcutaneous; 2/d, twice daily; 3/d, three times daily; NS, normal saline.