Table 2. Univariate and multivariate Cox proportional hazards regression analysis of risk factors of survival in colorectal cancer patients.
| Variables | Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | ||
| Elevated BRIX1 | 8.231 | 1.034–58.763 | 0.041 | 4.988 | 1.018–21.119 | 0.048 | |
| Age (years) | 1.029 | 0.968–1.094 | 0.357 | – | – | – | |
| Sex | 0.598 | 0.150–2.393 | 0.468 | – | – | – | |
| Rectal cancer | 1.195 | 0.531–2.691 | 0.667 | – | – | – | |
| Tumor stage III or IV | 9.517 | 1.170–77.402 | 0.035 | 6.711 | 1.097–36.184 | 0.044 | |
| Poor differentiation | 7.138 | 1.700–29.977 | 0.007 | 5.423 | 1.272–23.124 | 0.022 | |
| Elevated CEA | 0.766 | 0.183–3.206 | 0.715 | – | – | – | |
| Elevated CA199 | 0.615 | 0.147–2.575 | 0.506 | – | – | – | |
BRIX1, biogenesis of ribosomes BRX1; CA199, carbohydrate antigen 199; CEA, carcinoembryonic antigen; CI, confidence interval; HR, hazard ratio.