Table 2. Variable screening process related to CSS.

	Gray’s test			CSS univariant COX				CSS multivariant COX
	P value (CSS)	Filter results (P<0.2)		HR (95% CI)	P value (CSS)	Filter results (P<0.05)		HR (95% CI)	P value (CSS)	Filter results (P<0.05)
Sex	0.302
Race	0.213
Marital status	0.178	Chosen				Reject
Married				1	reference
Unmarried				0.73 (0.53, 1.01)	0.057
Unknown				0.73 (0.23, 2.32)	0.593
Grade	<0.001	Chosen				Chosen				Chosen
Unknown				1	reference			1	reference
I/II				0.53 (0.37, 0.77)	<0.001			0.53 (0.37, 0.77)	<0.001
III/IV				1.51 (1.00, 2.28)	0.051			1.51 (1.00, 2.28)	0.051
Surgery to LN	0.645
No
Yes
Unknown
Size group	<0.001	Chosen				Chosen				Chosen
0–20				1	reference			1	reference
21–50				1.92 (1.17, 3.14)	0.001			1.51 (0.64, 3.55)	0.346
51–100				5.05 (3.21, 7.97)	<0.001			3.46 (1.55, 7.71)	0.002
>100				5.19 (3.25, 8.28)	<0.001			5.46 (2.52, 11.86)	<0.001
Unknown				1.96 (0.86, 4.43)	0.108			3.50 (1.30, 9.39)	0.013
AFP	<0.001	Chosen				Chosen				Chosen
Positive				1	reference			1	reference
Negative				0.45 (0.31, 0.66)	<0.01			0.45 (0.31, 0.66)	<0.001
Unknown				0.44 (0.29, 0.68)	<0.01			0.44 (0.29, 0.68)	<0.001
Fibrosis Score	0.795
Fibrosis score 5–6
Fibrosis score 0–4
Unknown
Insurance	0.234
T stage	<0.001	Chosen				Chosen				Chosen
T1/0				1	reference
T2				1.87 (1.19, 2.92)	<0.001
T3				4.85 (3.23, 7.27)	<0.001
T4				8.67 (4.75, 15.85)	<0.001
TX				1.55 (0.55, 4.34)	0.402
N stage	0.010	Chosen				Chosen				Chosen
N0				1	reference
N1				1.76 (1.11, 2.79)	0.017
NX				2.00 (0.93, 4.29)	0.075
M stage	<0.001	Chosen				Chosen				Chosen
M0				1	reference
M1				3.49 (2.33, 5.24)	<0.001
MX				0.67 (0.09, 4.81)	0.693