Figure 5.
Effects of ESCO1 silencing on the metastatic potential in vitro. Cell migration assays for (A) PC3 and (B) Du145 cells. Cell invasion assays for (C) PC3 and (D) Du145 cells. Representative figures of each experiment are presented with the quantification of the number of migrating or invading tumor cells (magnification, ×200). *, P<0.05. Data are presented as the mean ± standard deviation of three independent experiments. ESCO1, establishment of sister chromatid cohesion N-acetyltransferase 1; shRNA, short hairpin RNA.