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. 2021 Jun;10(6):2882–2894. doi: 10.21037/tcr-20-1751

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2021 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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SLC26A6 is overexpressed in HCC tissues and correlates with poor survival. (A) Scatter plot showing the -log10 FDR values of the 417 SLC family genes when compared their expression between HCC and normal tissues from TCGA dataset. (B) Expression level of SLC26A6 in 30 paired HCC and para-tumor tissues from PUMCH cohort. (C) Representative photographs of SLC26A6 expression in TMA sections of normal liver, para-tumor and HCC tissues. (D) Comparison of H-scores of SLC26A6 between normal liver (n=37), para-tumor (n=31) and HCC tissues (n=165). (E,F) Kaplan-Meier curves for HCC patients in TCGA or PUMCH cohort by SLC26A6 mRNA or protein expression. ****, P<0.0001; **, P<0.01. HCC, hepatocellular carcinoma.