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. 2021 Feb;10(2):779–789. doi: 10.21037/tcr-20-2560

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2021 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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One patient experienced pseudoprogression of HER-2 negative AFP-producing gastric adenocarcinoma with multiple liver metastases. The patient was treated with Apatinib combined with anti-PD-1 antibody as third-line treatment. (A) The changes in target lesions evaluated on the basis of RECIST version 1.1. (B) The levels of serum AFP at different time points in the treatment process. (C) Radiographic images of liver metastases (arrows) at different time points. Anti-PD-1, anti-PD-1 antibody.