Table 3. Univariate and multivariate analysis with overall survival of M0 group.
| Characteristics | Univariate analysis | Multivariable analysis | |||
|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | ||
| Histology | |||||
| WMD | 1 | 1 | |||
| PD | 1.77 (1.62–1.93) | <0.001 | 1.28 (1.21–1.35) | <0.001 | |
| SRC | 1.78 (1.62–1.96) | <0.001 | 1.47 (1.37–1.57) | <0.001 | |
| SRC (vs. PD) | 1.01 (0.93–1.09) | 0.864 | |||
| Age (yrs) | |||||
| <70 | 1 | 1 | |||
| ≥70 | 1.34 (1.25–1.43) | <0.001 | 1.59 (1.48–1.70) | <0.001 | |
| Gender | |||||
| Male | 1 | ||||
| Female | 0.95 (0.89–1.02) | 0.153 | |||
| Race | |||||
| White | 1 | 1 | |||
| Black | 1.03 (0.94–1.14) | 0.531 | |||
| Othera | 0.73 (0.67–0.79) | <0.001 | 0.78 (0.72–0.85) | <0.001 | |
| Tumor stage | |||||
| T1 | 1 | 1 | |||
| T2/T3/T4 | 4.15 (3.67–4.71) | <0.001 | 2.49 (2.19–2.85) | <0.001 | |
| Node stage | |||||
| Negative | 1 | 1 | |||
| Positive | 3.55 (3.26–3.87) | <0.001 | 2.64 (2.41–2.89) | <0.001 | |
| Tumor location | |||||
| Upper stomach | 1 | 1 | |||
| Middle stomach | 0.81 (0.71–0.92) | 0.001 | 0.76 (0.67–0.87) | <0.001 | |
| Lower stomach | 0.87 (0.80–0.95) | 0.002 | 0.83 (0.76–0.91) | <0.001 | |
| Overlapping | 1.30 (1.16–1.47) | <0.001 | 1.02 (0.90– 1.15) | 0.808 | |
| Tumor size (cm) | |||||
| <5 | 1 | 1 | |||
| ≥5 | 1.72 (1.60–1.85) | <0.001 | 1.19 (1.11–1.28) | <0.001 | |
| Radiation | |||||
| No | 1 | ||||
| Yes | 1.02 (0.96–1.09) | 0.555 | |||
SRC, signet ring cell carcinoma; PD, poorly differentiated; WMD, well-to-moderately differentiated; HR, hazard ratio; CI, confidence interval; yrs, years; LN, lymph node. aincludes: American Indian/AK Native, Asian/Pacific Islander.