Table S1. Clinicopathological characteristics of M1 group.

Variables	Signet ring cell carcinoma (A) (N=4,059)			Well and moderately differentiated AC (B) (N=2,948)				Poorly differentiated AC (C) (N=6,362)
	N	%		N	%	P (A vs. B)		N	%	P (A vs. C)
Age (yrs)						<0.001				<0.001
Mean	57			64				61
SD	13.1			10.7				12.2
Gender						<0.001				<0.001
Male	2,016	49.7		2,228	75.6			4,318	67.9
Female	2,043	50.3		720	24.4			2,044	32.1
Race						<0.001				0.621
White	2,941	72.7		2,137	72.6			4,596	72.4
Black	490	12.1		478	16.2			807	12.7
Othera	616	15.2		328	11.1			944	14.9
T stage						<0.001				<0.001
T1	545	21.1		623	34.3			998	24.4
T2	217	8.4		87	4.8			247	6.0
T3	493	19.1		408	22.5			928	22.7
T4a	445	17.2		215	11.8			669	16.3
T4b	883	34.2		484	26.6			1,255	30.6
Node stage						0.014				0.067
N0	20	6.9		15	10.7			37	7.9
N1	17	5.8		15	10.7			45	9.6
N2	52	17.9		33	23.6			70	14.9
N3a	67	23.0		33	23.6			135	28.7
N3b	135	46.4		38	27.1			184	39.1
Surgery						<0.001				0.691
Yes	738	18.4		424	14.5			1,179	18.7
No	3,280	81.6		2,503	85.5			5,133	81.3
Examined LN						0.014				0.067
≥15	292	42.0		140	35.9			471	42.9
<15b	389	58.0		250	64.1			618	57.1
Tumor location						<0.001				0.878
Upper stomach	744	28.8		1,484	61.9			2,531	52.6
Middle stomach	531	20.6		241	10.1			584	12.1
Lower stomach	771	29.9		489	20.4			1,060	22.0
Overlapping	533	20.7		184	7.7			636	13.2
Tumor size (cm)						0.188				0.095
≥5	680	55.6		705	53.0			471	43.3
<5	542	44.4		624	47.0			618	56.7

yrs, years; SD, standard deviation; LN, lymph node. ^aincludes American Indian/AK Native, Asian/Pacific Islander; ^bexamined LN <15 was defined as pNx.