Table 1. Correlation of patient clinicopathological features with microvessel density (MVD) and carcinoembryonic antigen-associated cell adhesion molecule 1 (CEACAM1) expression in tumors.
| Variables | No. of patients | MVDa | CEACAM1 expressionb | |||||
|---|---|---|---|---|---|---|---|---|
| High MVD (%) | Low MVD (%) | P-valuec | High expression (%) | Low expression (%) | P-valuec | |||
| Total | 80 | 35 (43.8) | 45 (56.2) | 35 (43.8) | 45 (56.2) | |||
| Tumor staging | ||||||||
| pT1–pT2 | 58 | 23 (39.7) | 35 (60.3) | 0.23 | 24 (41.4) | 34 (58.6) | 0.49 | |
| pT3–pT4 | 22 | 12 (54.5) | 10 (45.5) | 11 (50.0) | 11 (50.0) | |||
| Lymph node involvement | ||||||||
| pN0 | 56 | 22 (39.3) | 34 (60.7) | 0.22 | 17 (30.4) | 39 (69.6) | 0.01 | |
| pN+ | 24 | 13 (54.2) | 11 (45.8) | 18 (75.0) | 6 (25.0) | |||
| Tumor grading | ||||||||
| G1 | 49 | 17 (34.7) | 32 (65.3) | 0.04 | 18 (36.7) | 31 (63.3) | 0.11 | |
| G2–G3 | 31 | 18 (58.1) | 13 (41.9) | 17 (54.8) | 14 (45.2) | |||
| Sex | ||||||||
| Male | 53 | 25 (47.2) | 28 (52.8) | 0.39 | 22 (37.7) | 31 (62.3) | 0.57 | |
| Female | 27 | 10 (37.0) | 17 (63.0) | 13 (55.6) | 14 (44.4) | |||
| Age | ||||||||
| ≤63 years | 42 | 20 (47.6) | 22 (52.4) | 0.46 | 18 (42.9) | 24 (57.1) | 0.86 | |
| >63 years | 38 | 15 (39.5) | 23 (60.5) | 17 (44.7) | 21 (55.3) | |||
a, MVD was categorized according to the median MVD of all tumors into low (< 30 microvessels/400× microscopic field of view) and high (≥30 microvessels/400× microscopic field of view); b, CEACAM1 expression was categorized into low (<66% of CEACAM1 positive tumor cells) and high (≥66% of CEACAM1 positive tumor cells); c, two-sided P-values were calculated by Pearson’s Chi-square test or Fisher’s exact test to evaluate significance of correlations.