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. 2021 Jun;10(6):2738–2746. doi: 10.21037/tcr-20-3385

Table 2. Univariate analysis and multivariate analysis in CHCC.

Variables Univariate analysis Multivariate analysis
HR (95% CI) P value HR (95% CI) P value
Age (≥60) 3.03 (1.15–7.97) 0.02 3.14 (1.16–8.49) 0.02
Gender (male) 0.90 (0.30–2.73) 0.85
Family cancer history (yes) 0.85 (0.27–2.67) 0.78
Serum AFP level (≥400) 1.61 (0.52–4.94) 0.41
Child-Pugh classification (B/A) 2.94 (0.82–10.60) 0.10 4.04 (0.94–17.30) 0.06
Pathologic stage (III + IV/I + II) 2.42 (0.80–7.36) 0.12
T stage (T3 + T4 + Tx/T1 + T2) 2.89 (0.95–8.78) 0.06 1.60 (0.44–5.85) 0.48
N stage (N1 + N2 + Nx/N0) 1.08 (0.35–3.38) 0.89
M stage (M1 + Mx/M0) 2.20 (0.77–6.30) 0.14
Vessels in tumor (Micro + Macro/none) 3.57 (1.44–8.86) <0.01 3.51 (1.28–9.62) 0.02
Recurrence (yes) 1.36 (0.52–3.60) 0.53
SOX9 (high expression) 0.55 (0.16–1.89) 0.34

CHCC, cirrhotic hepatocellular carcinoma; HR, hazard ratio; CI, confidence interval; AFP, α-fetoprotein; Micro, microvessels; Macro, macrovessels; SOX9, Sex-Determining Region Y-Box 9.