Table 2. Summary of the main clinical data of 89 cases in the literature.
Main clinical data | All patients, n (%) |
---|---|
Total of the number of cases | 89 |
Median age(years) | 70 |
Sex | |
Male | 67 (75.3) |
Female | 22 (24.7) |
Common findings of presentation | |
Papules, nodules, or plaque | 76 (85.4) |
Ulcer | 4 (4.5) |
Pustule | 1 (1.1) |
Others (such as unique subcutaneous swelling) | 6 (6.7) |
Data not available | 2 (2.2) |
Common findings of location | |
Extremities, trunk, chest or widespread | 72 (80.9) |
Other locations (face, nose, scalp, neck, feet, finger) | 10 (11.2) |
Data not available | 7 (7.9) |
Chronology of skin lesions | |
Before diagnosis of CMML | 5 (5.7) |
Concomitant with diagnosis of CMML | 26 (29.2) |
After diagnosis of CMML | 56 (62.9) |
Data not available | 2 (2.2) |
Extramedullary (EM) manifestations | |
Hepatosplenomegaly or lymphadenopathy | 64 (71.9) |
Central nervous system involvement | 1 (1.1) |
Testicular swelling | 1 (1.1) |
Parotid gland swelling | 1 (1.1) |
None | 5 (5.6) |
Data not available | 17 (19.1) |
Duration from skin lesion to disease progression or death(months) | |
≤5 | 30 (33.7) |
6-10 | 6 (6.7) |
10-20 | 28 (31.5) |
23 | 16 (18.0) |
Data not available | 9 (10.1) |
Treatment | |
Chemotherapy±radiotherapy or local steroid | 72 (80.9) |
Stem cell transplant | 1 (1.1) |
None or palliative care | 6 (6.7) |
Data not available | 10 (11.2) |
CMML, chronic myelomonocytic leukaemia.