Table 3. Multivariate analyses of OS in the SEER training set.
| Variables | Multivariate analysis | |
|---|---|---|
| HR (95% CI) | P value | |
| Age at diagnosis (years) | ||
| ≤44 | Reference | |
| 45–59 | 1.078 (0.118–0.635) | 0.525 |
| 60–74 | 1.331 (0.113–2.531) | 0.011 |
| ≥75 | 2.215 (0.113–7.021) | <0.001 |
| Sex | ||
| Female | Reference | |
| Male | 1.119 (0.052–2.170) | 0.030 |
| Tumor size (cm) | ||
| <3.7 | Reference | |
| 3.7–6.8 | 1.137 (0.059–2.193) | 0.028 |
| >6.8 | 1.110 (0.069–1.512) | 0.131 |
| Prime site of tumor | ||
| Cardia/fundus | Reference | |
| Middle of gastric bodya | 0.689 (0.063–5.935) | <0.001 |
| Antrum/pylorus | 0.762 (0.061–4.451) | <0.001 |
| AJCC T stage (8th) | ||
| T1 | Reference | |
| T2 | 1.152 (0.118–1.203) | 0.229 |
| T3 | 1.677 (0.098–5.288) | <0.001 |
| T4 | 2.363 (0.105–8.172) | <0.001 |
| AJCC N stage (8th) | ||
| N0 | Reference | |
| N1 | 1.709 (0.074–7.206) | <0.001 |
| N2 | 2.090 (0.075–9.882) | <0.001 |
| N3a | 2.661 (0.078–12.575) | <0.001 |
| N3b | 3.210 (0.098–11.870) | <0.001 |
| AJCC M stage (8th) | ||
| M0 | Reference | |
| M1 | 2.139 (0.071–10.784) | <0.001 |
a, middle of gastric body includes body of stomach, lesser curvature of stomach, and greater curvature of stomach. T, N, M stages come from AJCC. AJCC, American Joint Committee on Cancer; SEER, Surveillance, Epidemiology, and End Results.