Table 3. Treatment-related adverse events (TRAEs).
| Total (n=19), n (%) | ||
|---|---|---|
| Any grade | Grade 3/4 | |
| TRAEs | 3 (15.8) | 3 (15.8) |
| Common TRAE | ||
| Decreased appetite | 5 (26.3) | 0 |
| Diarrhea | 3 (15.8) | 0 |
| Nausea | 3 (15.8) | 0 |
| Fatigue | 6 (31.6) | 0 |
| Vomiting | 4 (21.1) | 0 |
| Abdominal pain | 3 (15.8) | 0 |
| Pyrexia | 1 (5.3) | 0 |
| Pruritus | 2 (10.5) | 1 (5.3) |
| Rash | 2 (10.5) | 1 (5.3) |
| Hand-foot syndrome | 4 (21.1) | 1 (5.3) |
| Proteinuria | 1 (5.3) | 0 |
| AST increase | 7 (36.8) | 1 (5.3) |
| Blood bilirubin increase | 6 (31.6) | 0 |
| ALT increase | 7 (36.8) | 1 (5.3) |
| Hematological AE | ||
| Platelet count decrease | 5 (26.3) | 0 |
| Leukopenia decrease | 4 (21.1) | 0 |
| Neutropenia decrease | 4 (21.1) | 0 |
| Hemoglobin decrease | 3 (15.8) | 0 |
| Additional TRAEs of special interest | ||
| Interstitial lung disease | 0 | 0 |
| Colitis | 0 | 0 |
| Hypopituitarism | 0 | 0 |
| Thyroid disorder | 8 (42.1) | 0 |
AE, adverse event; ALT, alanine aminotransferase; AST, aspartate aminotransferase.