Table 1. Co-culture compositions of M2-TAMs and osteosarcoma cells, with or without the addition of IL-1β, IL-1β receptor inhibitor or NF-κB inhibitor.
| Variables | IL-1β | IL-1β receptor inhibitor | NF-κB inhibitor |
|---|---|---|---|
| MG63 | M2-TAMs supernatant | M2-TAMs supernatant | M2-TAMs supernatant |
| M2-TAMs | M2-TAMs | M2-TAMs | |
| M2-TAMs supernatant + IL-1β | M2-TAMs supernatant + Anakinra | M2-TAMs supernatant + Rocaglamide A | |
| M2-TAMs + IL-1β | M2-TAMs + Anakinra | M2-TAMs + Rocaglamide A | |
| 143B | M2-TAMs supernatant | M2-TAMs supernatant | M2-TAMs supernatant |
| M2-TAMs | M2-TAMs | M2-TAMs | |
| M2-TAMs supernatant + IL-1β | M2-TAMs supernatant + Anakinra | M2-TAMs supernatant + Rocaglamide A | |
| M2-TAMs + IL-1β | M2-TAMs + Anakinra | M2-TAMs + Rocaglamide A |
TAMs, tumor-associated macrophages.