Table 3. All-cause mortality and chondrosarcoma-specific mortality for each prognostic factor and categorical variable.
Characteristics | All-cause mortality | Chondrosarcoma-specific mortality | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Total | Dead | Alive | P | Total | Dead | Alive | P | ||||||
N | % | N | % | N | % | N | % | ||||||
Total | 1,128 | 264 | 23.4 | 864 | 76.6 | – | 1,015 | 151 | 14.9 | 864 | 85.1 | – | |
Age at diagnosis (years) | <0.001 | <0.001 | |||||||||||
≤55 | 568 | 67 | 11.8 | 501 | 88.2 | 548 | 47 | 8.6 | 501 | 91.4 | |||
56–73 | 402 | 114 | 28.4 | 288 | 71.6 | 360 | 72 | 20.0 | 288 | 80.0 | |||
≥74 | 158 | 83 | 52.5 | 75 | 47.5 | 107 | 32 | 29.9 | 75 | 70.1 | |||
Gender | 0.002 | 0.011 | |||||||||||
Female | 493 | 94 | 19.1 | 399 | 80.9 | 452 | 53 | 11.7 | 399 | 88.3 | |||
Male | 635 | 170 | 26.8 | 465 | 73.2 | 563 | 98 | 17.4 | 465 | 82.6 | |||
Race | 0.708 | 0.460 | |||||||||||
White | 989 | 235 | 23.8 | 754 | 76.2 | 891 | 137 | 15.4 | 754 | 84.6 | |||
Black | 76 | 15 | 19.7 | 61 | 80.3 | 68 | 7 | 10.3 | 61 | 89.7 | |||
Other | 63 | 14 | 22.2 | 49 | 77.8 | 56 | 7 | 12.5 | 49 | 87.5 | |||
Primary site | <0.001 | <0.001 | |||||||||||
Upper limb | 216 | 32 | 14.8 | 184 | 85.2 | 198 | 14 | 7.1 | 184 | 92.9 | |||
Lower limb | 329 | 97 | 29.5 | 232 | 70.5 | 294 | 62 | 21.1 | 232 | 78.9 | |||
Axial | 468 | 119 | 25.4 | 349 | 74.6 | 418 | 69 | 16.5 | 349 | 83.5 | |||
Other | 115 | 16 | 13.9 | 99 | 86.1 | 105 | 6 | 5.7 | 99 | 94.3 | |||
Histological type | <0.001 | <0.001 | |||||||||||
Conventional chondrosarcoma | 934 | 164 | 17.6 | 770 | 82.4 | 856 | 86 | 10.0 | 770 | 90.0 | |||
Myxoid chondrosarcoma | 54 | 12 | 22.2 | 42 | 77.8 | 48 | 6 | 12.5 | 42 | 87.5 | |||
Dedifferentiated chondrosarcoma | 109 | 83 | 76.1 | 26 | 23.9 | 84 | 58 | 69.0 | 26 | 31.0 | |||
Other | 31 | 5 | 16.1 | 26 | 83.9 | 27 | 1 | 3.7 | 26 | 96.3 | |||
Grade | <0.001 | <0.001 | |||||||||||
I | 399 | 36 | 9.0 | 363 | 91.0 | 383 | 20 | 5.2 | 363 | 94.8 | |||
II | 480 | 95 | 19.8 | 385 | 80.2 | 429 | 44 | 10.3 | 385 | 89.7 | |||
III | 146 | 61 | 41.8 | 85 | 58.2 | 122 | 37 | 30.3 | 85 | 69.7 | |||
IV | 103 | 72 | 69.9 | 31 | 30.1 | 81 | 50 | 61.7 | 31 | 38.3 | |||
Tumor size (mm) | <0.001 | <0.001 | |||||||||||
≤72 | 554 | 67 | 12.1 | 487 | 87.9 | 519 | 32 | 6.2 | 487 | 93.8 | |||
73–117 | 223 | 60 | 26.9 | 163 | 73.1 | 199 | 36 | 18.1 | 163 | 81.9 | |||
≥118 | 204 | 90 | 44.1 | 114 | 55.9 | 171 | 57 | 33.3 | 114 | 66.7 | |||
Other | 147 | 47 | 32.0 | 100 | 68.0 | 126 | 26 | 20.6 | 100 | 79.4 | |||
Metastasis | <0.001 | <0.001 | |||||||||||
Yes | 68 | 57 | 83.8 | 11 | 16.2 | 60 | 49 | 81.7 | 11 | 18.3 | |||
No | 1060 | 207 | 19.5 | 853 | 80.5 | 955 | 102 | 10.7 | 853 | 89.3 | |||
Surgery | <0.001 | <0.001 | |||||||||||
Yes | 1014 | 202 | 19.9 | 812 | 80.1 | 923 | 111 | 12.0 | 812 | 88.0 | |||
No | 114 | 62 | 54.4 | 52 | 45.6 | 92 | 40 | 43.5 | 52 | 56.5 | |||
RT | <0.001 | <0.001 | |||||||||||
Yes | 159 | 62 | 39.0 | 97 | 61.0 | 135 | 38 | 28.1 | 97 | 71.9 | |||
No | 969 | 202 | 20.8 | 767 | 79.2 | 880 | 113 | 12.8 | 767 | 87.2 | |||
CT | <0.001 | <0.001 | |||||||||||
Yes | 84 | 54 | 64.3 | 30 | 35.7 | 76 | 46 | 60.5 | 30 | 39.5 | |||
No | 1044 | 210 | 20.1 | 834 | 79.9 | 939 | 105 | 11.2 | 834 | 88.8 | |||
Treatment method | <0.001 | <0.001 | |||||||||||
Surgery | 850 | 139 | 16.4 | 711 | 83.6 | 780 | 69 | 8.8 | 711 | 91.2 | |||
No surgery and no RT and no CT | 66 | 27 | 40.9 | 39 | 59.1 | 52 | 13 | 25.0 | 39 | 75.0 | |||
RT | 26 | 17 | 65.4 | 9 | 34.6 | 19 | 10 | 52.6 | 9 | 47.4 | |||
CT | 15 | 13 | 86.7 | 2 | 13.3 | 14 | 12 | 85.7 | 2 | 14.3 | |||
Surgery and RT | 102 | 27 | 26.5 | 75 | 73.5 | 88 | 13 | 14.8 | 75 | 85.2 | |||
Surgery and CT | 38 | 23 | 60.5 | 15 | 39.5 | 34 | 19 | 55.9 | 15 | 44.1 | |||
RT and CT | 7 | 5 | 71.4 | 2 | 28.6 | 7 | 5 | 71.4 | 2 | 28.6 | |||
Surgery and RT and CT | 24 | 13 | 54.2 | 11 | 45.8 | 21 | 10 | 47.6 | 11 | 52.4 |
RT, radiotherapy; CT, chemotherapy.