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. 2020 Jul;9(7):4250–4266. doi: 10.21037/tcr-20-357

Table 3. All-cause mortality and chondrosarcoma-specific mortality for each prognostic factor and categorical variable.

Characteristics All-cause mortality Chondrosarcoma-specific mortality
Total Dead Alive P Total Dead Alive P
N % N % N % N %
Total 1,128 264 23.4 864 76.6 1,015 151 14.9 864 85.1
Age at diagnosis (years) <0.001 <0.001
   ≤55 568 67 11.8 501 88.2 548 47 8.6 501 91.4
   56–73 402 114 28.4 288 71.6 360 72 20.0 288 80.0
   ≥74 158 83 52.5 75 47.5 107 32 29.9 75 70.1
Gender 0.002 0.011
   Female 493 94 19.1 399 80.9 452 53 11.7 399 88.3
   Male 635 170 26.8 465 73.2 563 98 17.4 465 82.6
Race 0.708 0.460
   White 989 235 23.8 754 76.2 891 137 15.4 754 84.6
   Black 76 15 19.7 61 80.3 68 7 10.3 61 89.7
   Other 63 14 22.2 49 77.8 56 7 12.5 49 87.5
Primary site <0.001 <0.001
   Upper limb 216 32 14.8 184 85.2 198 14 7.1 184 92.9
   Lower limb 329 97 29.5 232 70.5 294 62 21.1 232 78.9
   Axial 468 119 25.4 349 74.6 418 69 16.5 349 83.5
   Other 115 16 13.9 99 86.1 105 6 5.7 99 94.3
Histological type <0.001 <0.001
   Conventional chondrosarcoma 934 164 17.6 770 82.4 856 86 10.0 770 90.0
   Myxoid chondrosarcoma 54 12 22.2 42 77.8 48 6 12.5 42 87.5
   Dedifferentiated chondrosarcoma 109 83 76.1 26 23.9 84 58 69.0 26 31.0
   Other 31 5 16.1 26 83.9 27 1 3.7 26 96.3
Grade <0.001 <0.001
   I 399 36 9.0 363 91.0 383 20 5.2 363 94.8
   II 480 95 19.8 385 80.2 429 44 10.3 385 89.7
   III 146 61 41.8 85 58.2 122 37 30.3 85 69.7
   IV 103 72 69.9 31 30.1 81 50 61.7 31 38.3
Tumor size (mm) <0.001 <0.001
   ≤72 554 67 12.1 487 87.9 519 32 6.2 487 93.8
   73–117 223 60 26.9 163 73.1 199 36 18.1 163 81.9
   ≥118 204 90 44.1 114 55.9 171 57 33.3 114 66.7
   Other 147 47 32.0 100 68.0 126 26 20.6 100 79.4
Metastasis <0.001 <0.001
   Yes 68 57 83.8 11 16.2 60 49 81.7 11 18.3
   No 1060 207 19.5 853 80.5 955 102 10.7 853 89.3
Surgery <0.001 <0.001
   Yes 1014 202 19.9 812 80.1 923 111 12.0 812 88.0
   No 114 62 54.4 52 45.6 92 40 43.5 52 56.5
RT <0.001 <0.001
   Yes 159 62 39.0 97 61.0 135 38 28.1 97 71.9
   No 969 202 20.8 767 79.2 880 113 12.8 767 87.2
CT <0.001 <0.001
   Yes 84 54 64.3 30 35.7 76 46 60.5 30 39.5
   No 1044 210 20.1 834 79.9 939 105 11.2 834 88.8
Treatment method <0.001 <0.001
   Surgery 850 139 16.4 711 83.6 780 69 8.8 711 91.2
   No surgery and no RT and no CT 66 27 40.9 39 59.1 52 13 25.0 39 75.0
   RT 26 17 65.4 9 34.6 19 10 52.6 9 47.4
   CT 15 13 86.7 2 13.3 14 12 85.7 2 14.3
   Surgery and RT 102 27 26.5 75 73.5 88 13 14.8 75 85.2
   Surgery and CT 38 23 60.5 15 39.5 34 19 55.9 15 44.1
   RT and CT 7 5 71.4 2 28.6 7 5 71.4 2 28.6
   Surgery and RT and CT 24 13 54.2 11 45.8 21 10 47.6 11 52.4

RT, radiotherapy; CT, chemotherapy.