. 2020 Aug;9(8):4550–4562. doi: 10.21037/tcr-19-2873

Table S2. Identification of DEGs in TCGA.

DEGs	Gene names
Upregulated	AL121772.1, AL365356.4, B3GNT3, AC009065.5, ABCA12, AC020907.1, FXYD3,TSPAN1, AC093904.2, PPP1R14D, STYK1, SH3TC2, ZIC2, LINC00628, C2orf70, HIST1H2BD, CHRNA5, JPH1, SLC7A11, CKMT1A, HIST2H2BE, AFAP1-AS1, SPDEF, LINC00365, KCNK1, AC009065.2
Downregulated	CD5L, AC127496.1, AC091230.1, LMAN1L, FAM9C, SPIC, KCNT1, AC023154.1, STAB2, CD160, NKX2-5, SLC9A5, GPR182, CXCR2P1, AC008609.1, MMP12, NPIPA9, ITGAD, EEF1A1P24, IDI2-AS1, AC073850.1, KLRF1, SCN11A, ADRA1A, RF00100, LINC00996, UMODL1-AS1, DNASE1L3, GDF7, NR5A1, TBC1D27P, DNAH17-AS1, OR5G5P, H3F3C, FCRL3, PARP15, U62631.1, KLRD1, SIGLEC11, CCM2L, NCR1, AC245884.6, ABCA9-AS1, FGFBP2, AIF1L, LRTM1, LINC01894, KLHL14, CD22, LEFTY2, CRHBP, CR1, AP001605.1, TBX21, SNORD17, RN7SL752P, ATP4B, TRAPPC3L, KIR3DX1, AC009951.1, CR786580.1, AC007952.6, AL031658.1, TRG-AS1, FCRL2, AL137789.1, CLECL1, AC010970.1, LILRA1, TLR10, AC007728.2, CD36, TM4SF19, GLYCTK-AS1, AC012123.1, CHRNA4, FCRL6, AC112229.3, PTGDR, FCRL5, AC079015.1, KMO, IL9RP3, P2RX5, BFSP2, AL356234.1, ZBTB20-AS1, C11orf21, CASP16P, CFP, FGD2, KLRC4-KLRK1, PATL2, FGR, AC104809.1, LINC01537, LY86-AS1, TNFRSF13B, TLX1NB, LINC00528, LINC01684, AC010976.2, HIST2H3C, ADAD2, TEX101, ITGB2-AS1, FP671120.5, CD300LB, TDGF1, P2RX5-TAX1BP3, PARVG, BTG1P1, AC060234.2, SCIMP, HBA2, KRT72, TRDV1, BANK1, DEFA4, TXK, PZP, AC004687.1, NCF1C, MS4A1, NKG7, LILRB1, CHI3L1, MATK, FCRL1, Z84723.1, CNR2, NFIA-AS2, PAX5, ABHD17AP5, AL023653.1, KLRK1, ADGRE1, RPL7AP10, ZC3H12D, AC108206.1, AC018697.1, TSPAN32, POU2F2, TRGC1, OR5G3, HK3, RNU4-62P, LINC00173, CETP, WDFY4, SLC5A10, KIR2DL1, CD72, KCNJ10, TLX1, FAM53B-AS1, LINC01857, IL18RAP, DCSTAMP, LILRB5, NPY5R, KLRC4, AL137786.1, TMC8, CD19, KRT17P8, ITGAL, AC005332.2, CD52, CD244, Z97192.3, AC012645.3, LILRA4, HBB AL365475.1, KRT73, EOMES, AC004381.1, KEL, AC008033.3, AC018755.4, TRDC, HBA1, AL359885.1, PLEK, CD180, SASH3, CCL2, AC015660.4, ACAP1, BTK, MCOLN2, PSG9, AC010175.1, KLF1, PPP1R16B, UNC45B, COL4A3, C1QTNF1-AS1, CDHR1, AC008750.1, IL4I1, AL451067.1, IKZF3, BTLA, FCAMR, AC023510.2, TNFRSF13C, P2RY13, MAP4K1, LINC01781, AC008040.1, PRKCB, GDPD2, AP003086.1, BLK, SPATC1, HCG22, KRT75, AC243960.1, TPO, AMTN, BTBD6P1, TBC1D10C, LINC02245, C10orf90, CADM3-AS1, AC007386.1, MIR3609, FAM129C, SP140, SIGLEC22P, AC104809.2, FABP4, GPR18, GVINP1, HEATR9, TRGC2, GAPT, AC104024.1, NCF1, GPR55, AC099792.1, FCRLA, RASGRP2, GIMAP5, STAP1, AC063977.6, NPY1R, CDCA4P1, SEMA3D, MIR6774, CD37, RIPOR2, TEX53, AC079793.1, NOX5, TREML2, SCN4A, FAM30A, AC123912.4, CX3CR1, ACTG1P21, FAM238A, CARMIL2, SLC4A1, AC093010.1, AC064805.1, LINC00926, SIGLEC5, MTHFD2P1, SNORA73B, RN7SL5P, LINC00943, CCR6, GLYATL1B, LINC01645, TRAF3IP3, TTC24, LINC01215, E2F3P1, ZAP70, AL133371.2, RPL31P11, AC003957.1, AL121985.1, HLA-DOB, KRT79, AL161756.2, RSL24D1P11, AC023301.1, AC093010.2, LINC01010, SLC12A3, AL031595.1, AC119396.1, AC060764.1, AC016027.2, CELF2-AS1, SCARNA10, IRX6, LINC02422, AL096816.1, LINC01539, LINC00494, AL355076.3, PSG5, PIK3CD-AS1, HLA-DQB1-AS1, AL034397.3, AJAP1, PF4V1, AC103809.1, AL353801.1, DIRC3-AS1, AP000924.1, PTCRA, AL683807.1, CHI3L2, KIR3DL1, LTB, GGTLC1, AL356417.1, LINC01447, NCR3, LINC02137, SCNN1G, AC015909.3, AC092145.1, LINC02413, PGM5P3-AS1, OR52N4, FCMR, KIR2DL3, DDX11L10, HMGN2P19, TRGV4, AC079584.2, LINC02576, RETN, AC010247.1, CCL14, TNXA, CXCR5, AL645608.2, REELD1, AC119428.2, EIF3FP1, AC073072.1, AC098935.2, AC015911.6, ALAS2, LINC01800, ITPKB-IT1, AC103858.1, CXCL6, C12orf42, CD27, PRAMENP, AC009970.1, CAMP, CLEC17A, SIRPG-AS1, IGHJ3P, FCER2, GTSF1L, CPN2, CCDC26, SIGLEC14, CD79B, AC083949.1, TBATA, TRGV3, AC008649.1, AC016168.1, AC007381.1, AL512378.1, SCARNA5, PCDH11X, DEFA3, AIM2, ANKRD20A19P, SLC7A10, AL031733.2, SNORA54, AL121985.3, AC243960.7, FCRL4, AC104699.1, AL161781.2, MIR4538, AC008878.3, TM4SF19-TCTEX1D2, TRAV1-1 LINC02397, SERPINA9, IL13, SIRPB3P, HLA-DQA2, SPATA21, CD79A, ZNF560, IL24, BEND4, LINC02132, CR2, AC105105.1, MIR4537, AP002957.1, TNMD, SNORD15B, AP001994.1, AC104971.3, LINC02244, AL162457.1, DNAH8, AC006946.3, RNU4-2, AL031429.1, ZNF80

DEGs

Gene names

Upregulated

AL121772.1, AL365356.4, B3GNT3, AC009065.5, ABCA12, AC020907.1, FXYD3,TSPAN1, AC093904.2, PPP1R14D, STYK1, SH3TC2, ZIC2, LINC00628, C2orf70, HIST1H2BD, CHRNA5, JPH1, SLC7A11, CKMT1A, HIST2H2BE, AFAP1-AS1, SPDEF, LINC00365, KCNK1, AC009065.2

Downregulated

CD5L, AC127496.1, AC091230.1, LMAN1L, FAM9C, SPIC, KCNT1, AC023154.1, STAB2, CD160, NKX2-5, SLC9A5, GPR182, CXCR2P1, AC008609.1, MMP12, NPIPA9, ITGAD, EEF1A1P24, IDI2-AS1, AC073850.1, KLRF1, SCN11A, ADRA1A, RF00100, LINC00996, UMODL1-AS1, DNASE1L3, GDF7, NR5A1, TBC1D27P, DNAH17-AS1, OR5G5P, H3F3C, FCRL3, PARP15, U62631.1, KLRD1, SIGLEC11, CCM2L, NCR1, AC245884.6, ABCA9-AS1, FGFBP2, AIF1L, LRTM1, LINC01894, KLHL14, CD22, LEFTY2, CRHBP, CR1, AP001605.1, TBX21, SNORD17, RN7SL752P, ATP4B, TRAPPC3L, KIR3DX1, AC009951.1, CR786580.1, AC007952.6, AL031658.1, TRG-AS1, FCRL2, AL137789.1, CLECL1, AC010970.1, LILRA1, TLR10, AC007728.2, CD36, TM4SF19, GLYCTK-AS1, AC012123.1, CHRNA4, FCRL6, AC112229.3, PTGDR, FCRL5, AC079015.1, KMO, IL9RP3, P2RX5, BFSP2, AL356234.1, ZBTB20-AS1, C11orf21, CASP16P, CFP, FGD2, KLRC4-KLRK1, PATL2, FGR, AC104809.1, LINC01537, LY86-AS1, TNFRSF13B, TLX1NB, LINC00528, LINC01684, AC010976.2, HIST2H3C, ADAD2, TEX101, ITGB2-AS1, FP671120.5, CD300LB, TDGF1, P2RX5-TAX1BP3, PARVG, BTG1P1, AC060234.2, SCIMP, HBA2, KRT72, TRDV1, BANK1, DEFA4, TXK, PZP, AC004687.1, NCF1C, MS4A1, NKG7, LILRB1, CHI3L1, MATK, FCRL1, Z84723.1, CNR2, NFIA-AS2, PAX5, ABHD17AP5, AL023653.1, KLRK1, ADGRE1, RPL7AP10, ZC3H12D, AC108206.1, AC018697.1, TSPAN32, POU2F2, TRGC1, OR5G3, HK3, RNU4-62P, LINC00173, CETP, WDFY4, SLC5A10, KIR2DL1, CD72, KCNJ10, TLX1, FAM53B-AS1, LINC01857, IL18RAP, DCSTAMP, LILRB5, NPY5R, KLRC4, AL137786.1, TMC8, CD19, KRT17P8, ITGAL, AC005332.2, CD52, CD244, Z97192.3, AC012645.3, LILRA4, HBB AL365475.1, KRT73, EOMES, AC004381.1, KEL, AC008033.3, AC018755.4, TRDC, HBA1, AL359885.1, PLEK, CD180, SASH3, CCL2, AC015660.4, ACAP1, BTK, MCOLN2, PSG9, AC010175.1, KLF1, PPP1R16B, UNC45B, COL4A3, C1QTNF1-AS1, CDHR1, AC008750.1, IL4I1, AL451067.1, IKZF3, BTLA, FCAMR, AC023510.2, TNFRSF13C, P2RY13, MAP4K1, LINC01781, AC008040.1, PRKCB, GDPD2, AP003086.1, BLK, SPATC1, HCG22, KRT75, AC243960.1, TPO, AMTN, BTBD6P1, TBC1D10C, LINC02245, C10orf90, CADM3-AS1, AC007386.1, MIR3609, FAM129C, SP140, SIGLEC22P, AC104809.2, FABP4, GPR18, GVINP1, HEATR9, TRGC2, GAPT, AC104024.1, NCF1, GPR55, AC099792.1, FCRLA, RASGRP2, GIMAP5, STAP1, AC063977.6, NPY1R, CDCA4P1, SEMA3D, MIR6774, CD37, RIPOR2, TEX53, AC079793.1, NOX5, TREML2, SCN4A, FAM30A, AC123912.4, CX3CR1, ACTG1P21, FAM238A, CARMIL2, SLC4A1, AC093010.1, AC064805.1, LINC00926, SIGLEC5, MTHFD2P1, SNORA73B, RN7SL5P, LINC00943, CCR6, GLYATL1B, LINC01645, TRAF3IP3, TTC24, LINC01215, E2F3P1, ZAP70, AL133371.2, RPL31P11, AC003957.1, AL121985.1, HLA-DOB, KRT79, AL161756.2, RSL24D1P11, AC023301.1, AC093010.2, LINC01010, SLC12A3, AL031595.1, AC119396.1, AC060764.1, AC016027.2, CELF2-AS1, SCARNA10, IRX6, LINC02422, AL096816.1, LINC01539, LINC00494, AL355076.3, PSG5, PIK3CD-AS1, HLA-DQB1-AS1, AL034397.3, AJAP1, PF4V1, AC103809.1, AL353801.1, DIRC3-AS1, AP000924.1, PTCRA, AL683807.1, CHI3L2, KIR3DL1, LTB, GGTLC1, AL356417.1, LINC01447, NCR3, LINC02137, SCNN1G, AC015909.3, AC092145.1, LINC02413, PGM5P3-AS1, OR52N4, FCMR, KIR2DL3, DDX11L10, HMGN2P19, TRGV4, AC079584.2, LINC02576, RETN, AC010247.1, CCL14, TNXA, CXCR5, AL645608.2, REELD1, AC119428.2, EIF3FP1, AC073072.1, AC098935.2, AC015911.6, ALAS2, LINC01800, ITPKB-IT1, AC103858.1, CXCL6, C12orf42, CD27, PRAMENP, AC009970.1, CAMP, CLEC17A, SIRPG-AS1, IGHJ3P, FCER2, GTSF1L, CPN2, CCDC26, SIGLEC14, CD79B, AC083949.1, TBATA, TRGV3, AC008649.1, AC016168.1, AC007381.1, AL512378.1, SCARNA5, PCDH11X, DEFA3, AIM2, ANKRD20A19P, SLC7A10, AL031733.2, SNORA54, AL121985.3, AC243960.7, FCRL4, AC104699.1, AL161781.2, MIR4538, AC008878.3, TM4SF19-TCTEX1D2, TRAV1-1 LINC02397, SERPINA9, IL13, SIRPB3P, HLA-DQA2, SPATA21, CD79A, ZNF560, IL24, BEND4, LINC02132, CR2, AC105105.1, MIR4537, AP002957.1, TNMD, SNORD15B, AP001994.1, AC104971.3, LINC02244, AL162457.1, DNAH8, AC006946.3, RNU4-2, AL031429.1, ZNF80

A total of 446 DEGs were identified, including 26 upregulated genes and 420 downregulated genes. TCGA, The Cancer Genome Atlas; DEGs, differentially expressed genes.