Table 2. Univariate analysis for the association between clinical characteristics and survival in metastatic PDAC patients.
Variables | Category | n | Univariate analysis | ||
---|---|---|---|---|---|
HR | 95% CI | P value | |||
PLR | ≤123 | 57 | 1 | ||
>123 | 77 | 1.581 | 1.092–2.287 | 0.015* | |
Age | – | 1 | |||
Increasing | 1.003 | 0.981–1.025 | 0.787 | ||
Gender | Male | 89 | 1 | ||
Female | 45 | 0.603 | 0.411–0.886 | 0.010* | |
KPS | 90 | 111 | 1 | ||
80 | 19 | 1.103 | 0.673–1.809 | 0.696 | |
70 | 4 | 2.480 | 0.904–6.803 | 0.078 | |
Location | Head | 44 | 1 | ||
Body/tail | 90 | 1.150 | 0.786–1.684 | 0.471 | |
Chemotherapy | Monotherapy | 42 | 1 | ||
Combined therapy | 92 | 0.595 | 0.407–0.870 | 0.007** |
*, P<0.05; **, P<0.01. PDAC, pancreatic ductal adenocarcinoma; HR, hazards ratio; PLR, platelet to lymphocyte ratio; KPS, Karnofsky Performance Status.