Table 1. Patients with primary melanoma of the breast reported in the literature.
| Reference | Age (years) | Size (cm) | Location (quadrant) | LN/metastases | BRAF mutations | Treatment | Outcome |
|---|---|---|---|---|---|---|---|
| (10) | 26 | 3.0 | L upper inner | Yes | NA | None | Died in 2 months |
| (4) | 50 | 1.2 | R | No | V600E | Breast-conserving surgery + SLNB + adjuvant IFN-a for 9 months | NED at 12 months |
| (3) | 54 | 10.0 | L upper outer | No | NA | Right mastectomy + AIND + one-stage reconstruction | NED at 6 months |
| (12) | 59 | 4.0 | L nipples | Yes | NA | Right mastectomy + AIND + chemotherapy | NED at 7 years |
| (11) | 70 | 2.1 | R upper inner quadrant | No | V600E | Breast-conserving surgery + SLNB | survival at 26 months |
| (11) | 30 | 3.0 | L | Axillary node | V600E | Breast-conserving surgery + AIND | After 8 months lost to follow-up |
L, left; R, right; NA, not available; IFN-a, interferon a; NED, no evidence of disease; OS, overall survival; AIND, axillary lymph node dissection; SLNB, sentinel lymph node biopsy.