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. 2021 Jul;10(7):3548–3559. doi: 10.21037/tcr-21-559

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2021 Translational Cancer Research. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

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miR-138 is down-regulated in CRC tissues and cell lines. (A) Relative expression of miR-138 in 30 pairs of CRC tumors compared with their adjacent normal tissues; (B) relative expression of miR-138 in five CRC cell lines (SW480, HT-29, SW620, HCT-8, RKO) and the relative expression level of miR-138 in eight colon cancer cell lines and normal colorectal epithelial cell lines CCD-18Co by quantitative RT-PCR. Each experiment was repeated three times, then the deviations were eliminated and the average value was taken (**P<0.01, ***P<0.001).