Table 2.
Information table of SHD targets.
| Targets | Protein names | UniProt ID |
|---|---|---|
| ABCB1 | ATP-dependent translocase ABCB1 | P08183 |
| ABCC1 | Multidrug resistance-associated protein 1 | P33527 |
| ABCG2 | Broad substrate specificity ATP-binding cassette transporter ABCG2 | Q9UNQ0 |
| ALB | Albumin | P02768 |
| ALDH2 | Aldehyde dehydrogenase | P05091 |
| ALOX15 | Polyunsaturated fatty acid lipoxygenase ALOX15 | P16050 |
| ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P09917 |
| APP | Amyloid-beta precursor protein | P05067 |
| BCL2 | Apoptosis regulator Bcl-2 | P10415 |
| CA1 | Carbonic anhydrase 1 | P00915 |
| CA2 | Carbonic anhydrase 2 | P00918 |
| CYP19A1 | Aromatase | P11511 |
| CYP1A1 | Cytochrome P450 1A1 | P04798 |
| CYP3A4 | Cytochrome P450 3A4 | P08684 |
| DLG4 | Disks large homolog 4 | P78352 |
| EPHX2 | Bifunctional epoxide hydrolase 2 | P34913 |
| ESR1 | Estrogen receptor | P03372 |
| ESR2 | Estrogen receptor beta | Q92731 |
| F3 | Tissue factor | P13726 |
| FABP4 | Fatty acid-binding protein | P15090 |
| FOS | Proto-oncogene c-Fos | P01100 |
| GAMT | Guanidinoacetate N-methyltransferase | Q14353 |
| HMGCR | 3-Hydroxy-3-methylglutaryl-coenzyme A reductase | P04035 |
| JUN | Transcription factor AP-1 | P05412 |
| KCND3 | Potassium voltage-gated channel subfamily D member 3 | Q9UK17 |
| KCNH2 | Potassium voltage-gated channel subfamily H member 2 | Q12809 |
| LCN2 | Neutrophil gelatinase-associated lipocalin | P80188 |
| MAPK14 | Mitogen-activated protein kinase 14 | Q16539 |
| MAPT | Microtubule-associated protein tau | P10636 |
| MMP2 | Matrix metalloproteinase-2 | P08253 |
| MMP9 | Matrix metalloproteinase-9 | P14780 |
| NFE2L2 | Nuclear factor erythroid 2-related factor 2 | Q16236 |
| NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 |
| NOX4 | NADPH oxidase 4 | Q9NPH5 |
| OPRM1 | Mu-type opioid receptor | P35372 |
| PPARA | Peroxisome proliferator-activated receptor alpha | Q07869 |
| PPARD | Peroxisome proliferator-activated receptor delta | Q03181 |
| PPARG | Peroxisome proliferator-activated receptor gamma | P37231 |
| PRKCA | Protein kinase C alpha type | P17252 |
| PTGES | Prostaglandin E synthase | O14684 |
| PTGS1 | Prostaglandin G/H synthase 1 | P23219 |
| PTGS2 | Prostaglandin G/H synthase 2 | P35354 |
| SLC18A2 | Synaptic vesicular amine transporter | Q05940 |
| TERT | Telomerase reverse transcriptase | O14746 |
| TLR2 | Toll-like receptor 2 | O60603 |
| TNKS | Poly [ADP-ribose] polymerase tankyrase-1 | O95271 |
| TTR | Transthyretin | P02766 |