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. Author manuscript; available in PMC: 2022 Jan 28.
Published in final edited form as: J Periodontal Res. 2021 Feb 26;56(3):501–511. doi: 10.1111/jre.12850

FIGURE 3.

FIGURE 3

The effect of IL-1B(3954)-SNP on both GCF amount (A) and concentration (B) of IL-1β and number (n) of red complex bacteria species (P.gingivalis, T.forsythia, T.denticola) in periodontitis sites. Both IL-1B(3954)-SNP and number of red complex bacteria species had significant effects on the IL-1β GCF amount and concentration. After controlling for IL-1B(3954)-SNP, periodontitis sites with three red complex bacteria species present had 4.7 times higher IL-1β GCF amount and 4.6 times higher IL-1β GCF concentration compared to periodontitis sites with one of red complex bacteria species present. After controlling for red complex bacteria species, periodontitis sites from subjects with IL-1B(3954)-SNP positive had 2.3 times higher IL-1β GCF amount and 2.4 times higher IL-1β GCF concentration compared to periodontitis sites from subjects with IL-1B(3954)-SNP negative.