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. 2021 Dec 29;13(12):e20810. doi: 10.7759/cureus.20810

Table 3. The Impact of Blood Type on Reactogenicity With the Second Dose of Vaccine.

1Statistics presented: Mean (SD); 2Statistical tests performed: Kruskal-Wallis test

  Blood Type  
Characteristic Overall, N = 3,7001 A, N = 9951 AB, N = 1481 B, N = 3691 O, N = 1,3661 Unknown, N = 8221 p-value2
Injection site pain 3.1 (2.84) 3.1 (2.74) 2.9 (2.79) 2.8 (2.79) 3.2 (2.83) 3.1 (3.00) 0.048
Injection site redness 0.7 (1.93) 0.7 (1.88) 0.3 (0.96) 0.7 (1.97) 0.8 (1.99) 0.8 (2.01) 0.3
Injection site swelling 0.8 (2.01) 0.8 (1.99) 0.4 (1.17) 0.7 (2.03) 0.8 (2.05) 0.8 (2.06) 0.2
Fatigue 3.4 (3.49) 3.5 (3.45) 3.0 (3.30) 3.1 (3.46) 3.5 (3.53) 3.3 (3.51) 0.2
Headache 2.2 (3.12) 2.2 (3.05) 1.7 (2.71) 2.0 (3.05) 2.2 (3.20) 2.3 (3.14) 0.3
Muscle pain 2.3 (3.28) 2.3 (3.24) 1.7 (2.82) 2.1 (3.23) 2.3 (3.31) 2.2 (3.34) 0.2
Chills 1.9 (3.20) 1.9 (3.23) 1.2 (2.50) 1.8 (3.24) 1.9 (3.22) 1.9 (3.20) 0.3
Joint pain 1.5 (2.95) 1.6 (2.98) 1.2 (2.68) 1.3 (2.80) 1.5 (3.00) 1.5 (2.96) 0.6
Fever 1.2 (2.64) 1.2 (2.70) 0.6 (1.88) 1.0 (2.43) 1.2 (2.69) 1.2 (2.69) 0.059
Nausea 0.6 (1.93) 0.6 (1.98) 0.3 (1.39) 0.5 (1.63) 0.6 (1.93) 0.7 (2.06) 0.11
Vomiting 0.1 (0.87) 0.1 (0.94) 0.1 (0.52) 0.1 (0.88) 0.1 (0.83) 0.1 (0.92) >0.9
Swollen lymph nodes 0.5 (1.77) 0.5 (1.85) 0.3 (1.44) 0.4 (1.69) 0.5 (1.85) 0.4 (1.60) 0.5
Sore throat 0.3 (1.27) 0.2 (1.19) 0.1 (0.66) 0.3 (1.52) 0.3 (1.21) 0.3 (1.42) 0.2