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. 2022 Jan 24;28(1):71–80. doi: 10.1038/s41591-021-01641-x

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© The Author(s) 2022, corrected publication 2022

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Extended Data Fig. 1 — Clinical and laboratory features of patients with WAS before and after GT: light pink: no disease; pink: mild disease; light red: moderate disease; red: severe disease. Eczema was graded with the SCORAD tool24. Infections and bleeding were graded in terms of recurrence and severity. Vasculitis was assessed according to the WAS severity scoring system4. Thrombocytopenia was defined as follows: grade 3 for a platelet count <10,000/µL; grade 2 between 10,000/µL and 20,000/µL; grade 1 between 20,000/µL and 50,000/µL. Grey box: not applicable. Statistical significance was determined by t test (***p < 0.001); NS: not significant.