Fig E5.

SARS-CoV-2 neutralization titer (NT90) analysis with serum samples from recovered COVID-19 patients (n = 24) against SARS-CoV-2 WT, Alpha, Alpha-E484K, Beta, and Delta variants. A, Percentages of vaccinees who tested positive (NT90 ≥ 1:16), borderline (1:16 > NT90 ≥ 1:8), or negative (NT90 < 1:8) for NT90 neutralization against SARS-CoV-2 WT and variants. B, Individual NT90 serum dilutions against SARS-CoV-2 WT and variants. Statistical significance between WT and variants was determined by Mann-Whitney U test for nonparametric distribution (∗P < .05). Medians are visualized as red lines together with the interquartile range as error bars. The cutoff value is illustrated by a gray dashed line.C, Determination of NT90 fold changes of SARS-CoV-2 variants relative to WT.