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. 2022 Jan 28;8:41. doi: 10.1038/s41420-022-00813-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — A mRNA expression of KLF2, IRF4, HDAC7, caspase-3, Bax, and Bcl-2; (B). protein expression of KLF2, IRF4, HDAC7, caspase-3, Bax, and Bcl-2; (C) Neuron survival after OGD treatment for 0, 24, 48, and 72 h determined by MTT assay in OGD-treated neurons; (D) Neuron apoptosis determined by flow cytometry 48 h after OGD; (E) Average neurite length and average number of primary neurites determined by immunofluorescence; *p < 0.05 vs. oe-NC + sh-NC; #p < 0.05 vs. oe-KLF2 + sh-NC. Data are expressed as mean ± standard deviation. Data from two groups were compared by independent sample t test. Data from multiple groups were compared by one-way ANOVA followed by Tukey’s post hoc test. Data comparison between groups at different time points was performed by repeated measure ANOVA followed by Tukey’s post hoc test.