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. 2022 Jan 28;7:9. doi: 10.1038/s41525-021-00277-7

Fig. 10. Mitochondrial complex I proteome is restored in SSO1 treated affected fibroblasts.

Fig. 10

a Volcano plot expressing quantitative proteomics data showing a decreased abundance of TIMMDC1 and other complex I subunits in patient III-2 relative to healthy control (n = 5) whole fibroblasts. b Volcano plot showing increased abundance of TIMMDC1 and other complex I subunits in SSO1 relative to NC5 treated patient III-2 or c III-6 whole fibroblasts. Horizontal line within the volcano plots represents a significance of p = 0.05 and vertical lines represent a fold-change of ±1.5. Blue = complex I subunits.