Table 2.
Immunophenotyping in CLL-HRS compared to CLL-HL.
| Stain | CLL-HRS* | CLL-HL* | p-value |
|---|---|---|---|
| Positive/total(%) | Positive/total (%) | ||
| EBER-ISH | 13/16 (81) | 17/27 (63) | 0.31 |
| CD30 | 16/16 (100) | 30/31 (97) | 1.0 |
| CD15 | 8/16 (50) | 24/31 (77) | 0.06** |
| CD20 | 7/17 (41) | 2/29 (7) | 0.01 |
| CD45 | 0/15 (0) | 0/31 (0) | 1.0 |
| PAX5 | 16/16 (100) | 26/28 (93) | 0.53 |
CLL-HRS Chronic lymphocytic leukemia/small lymphocytic lymphoma with Hodgkin/Reed–Sternberg-like cells, CLL-HL Classic Hodgkin lymphoma, EBER Epstein Barr Virus encoded RNA, ISH in situ hybridization.
*Cases with both CLL-HRS and CLL-HL areas are included in both totals.
**Most p-values based on Fisher’s exact test; one based on Chi-square test.